Have you brought debilitating symptoms to a health professional only to hear “ibuprofen and rest should do the trick” or worse yet, “It’s all in your head.”

We believe that understanding how your body affects your mind at different times of the month is a crucial first step in relieving PMS and taking back control of your life.

We are committed to empowering you with the scientific tools you need to understand how your biology impacts your emotions and how to feel your best all month long.

Our Clinical Trial

That’s why we ensured Jubilance passed the test of multiple gold-standard clinical trials with double-blinded placebo-controls and rigorous peer-review.

Read all the details of the landmark clinical trials of Jubilance and how the active ingredient in Jubilance, thermally stabilized oxaloacetate, relieves PMS.

CLINICAL TRIAL DATA

SEE THE RESEARCH

During PMS, hormone levels in some women can shift. This shift causes other parts of the body, especially the uterus and surrounding areas, to require more energy than normal. A region of the brain called the cerebellum, particularly sensitive to shifts in glucose supply, is left with less than it normally has the rest of the month.

Hence why you may have ravenous carb and fat cravings, which is essentially your cerebellum yelling, “I need more energy NOW!”

When the cerebellum doesn’t have enough energy to function properly, it can’t perform one of it’s primary jobs properly: emotional regulation.

This is the major cause of PMS anxiety, along with a host of other unwanted reactions like sadness, irritability, stress and mood swings.

Oxaloacetate supplementation increases cellular uptake of glucose including direct increase of brain glucose uptake. This increase in cellular uptake of glucose in the brain provides the extra energy your cerebellum needs to continue functioning normally.

That means you achieve the emotional stability, and the level of anxiety, that you feel during your best times of the month, all month long. (And many women report an overall improvement as well).

Oxaloacetate has also been shown to work in the liver to support the process of turning fatty acids into glucose.

Improved fatty acid metabolism means that more glucose energy is readily available for the cerebellum when it needs it most.

When your cerebellum has the extra energy it needs to regulate your emotions properly, you get your best self back.

When glutamate levels are too high and GABA levels are too low, the brain goes into overdrive with anxiety, racing thoughts, and overreactions to stimuli.

Oxaloacetate has been shown to reduce excess glutamate levels and increase GABA levels in the brain via “glutamate scavenging.”

While in your bloodstream, oxaloacetate binds to glutamate. The body, sensing the lower glutamate levels, sends excess glutamate across the blood-brain-barrier into the body, bringing the GABA-glutamate levels in the brain back into balance.

This is why clinical trials show that oxaloacetate helps balance GABA and glutamate levels to improve PMS anxiety.

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